Subversion of immunity by schistosomes – RETRACTED

Abstract

Chronic parasitic disease affects millions of people worldwide with an overwhelming burden on children. Helminth infections frequently cause chronic disease that may range from asymptomatic to debilitating. Schistosoma mansoni is a blood fluke that resides in the mesenterial veins of the host, causes chronic disease and has evolved to evade and exploit the immune system. This article discusses the state of our understanding of the complex regulation and control of immune responses induced by schistosomes.